身居纽约的人类学家葛瑞拉（Lorraine De Selle 饰）和兄长鲁迪（Danilo Mattei 饰）、好友派特（Zora Kerova 饰）结伴前往亚马逊丛林考察土著的生活习俗。抵达目的地后，他们遇见两个躲避外界追杀的毒贩：麦克（Giovanni Lombardo Radice 饰）和乔（Walter Lucchini 饰）。这两个邪恶的家伙利用当地人帮他们从事毒品生产和交易，稍不顺心便对当地人打骂对待。
正所谓恶贯满盈，善恶有报。麦克因残酷杀害包括土著首领女儿在内的当地人，而激起这群善良人的愤怒。他们拿起武器，对这些入侵的白人展开报复，而葛瑞拉他们也被牵连其中……
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